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1-6 Radical-7 Signal Extraction Pulse CO-Oximeter Operator’s Manual

Overview

light through the site to a diode (detector). Signal data is obtained by passing various visible

and infrared lights (LEDs, 500 to 1400nm) through a capillary bed (for example, a ﬁ ngertip, a

hand, a foot) and measuring changes in light absorption during the blood pulsatile cycle. This

information may be useful to clinicians. The maximum radiant power of the strongest light is rated

at ≤ 25 mW. The detector receives the light, converts it into an electronic signal and sends it to

the Radical-7 for calculation.

Carboxyhemoglobin

Oxyhemoglobin

Methemoglobin

Deoxyhemoglobin

Absorption Spectra

Plasma

Absorption (1/mm)

0.5

600 800

1.0

1.5

2.0

2.5

3.0

3.5

4.0

1000 1200 1400 1600

Wavelength (nm)

Once the Radical-7 receives the signal from the sensor, it utilizes Masimo Rainbow SET signal

extraction technology to calculate the patient’s functional oxygen saturation (SpO

(%)), blood

levels of carboxyhemoglobin (SpCO (%)), methemoglobin (SpMet (%)), Total Hemoglobin

concentration (SpHb (g/dl)) and pulse rate (PR (BPM)). The SpCO, SpMet and SpHb measurements

rely on a multiwavelength calibration equation to quantify the percentage of carbon monoxide

and methemoglobin and the concentration of total hemoglobin in arterial blood. In an ambient

temperature of 35º C the maximum skin surface temperature has been measured at less than 106º

F (41º C), veriﬁ ed by Masimo sensor skin temperature test procedure.

FUNCTIONAL SATURATION

The Radical-7 is calibrated to measure and display functional saturation (SpO

): the amount

of oxyhemoglobin expressed as a percentage of the hemoglobin that is available to transport

oxygen. Note that carboxyhemoglobin is not capable of transporting oxygen, but is recognized

as oxygenated hemoglobin by conventional pulse oximetry.

1. Light Emitting Diodes (LEDs)

(7 + wavelengths)

2. Detector

RADICAL-7 vs. DRAWN WHOLE BLOOD MEASUREMENTS

When SpO

, SpCO, SpMet and SpHb measurements obtained from the Radical-7 (non-

invasive) are compared to drawn whole blood (invasive) measurements by blood gas and/or

laboratory CO-Oximetry methods, caution should be taken when evaluating and interpreting

the results. The blood gas and/or laboratory CO-Oximetry measurements may differ from the

SpO

, SpCO, SpMet, SpHb and SpOC measurements of the Radical-7 Pulse CO-Oximeter.

In the case of SpO

, different results are usually obtained from the arterial blood gas sample if

the calculated measurement is not appropriately corrected for the effects of variables that shift

the relationship between the partial pressure of oxygen (PO

) and saturation, such as: pH,

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